 RESEARCH COURSES
Biological Sciences offers a wide array of research-based courses for undergraduates. The list below highlights some of our more popular research courses with information on when they are offered and how students go about enrolling in the course.
BIOL 15. Undergraduate Research Reports 1-unit seminar offered every quarter.
Undergraduate students who work in faculty research laboratories present the results of their projects. Organized by the Minority Undergraduate Research Program and the Minority Access to Research Careers Program. Designed for students with membership in the above-mentioned programs. Prerequisite(s): qualifications as determined by instructor at first class meeting. May be repeated for credit. Instructors: Barry Bowman, Al Zahler
BIOL 21L. Environmental Phage Genomics Laboratory 2-unit lab offered every quarter (not summer).
Introduction to hypothesis-driven laboratory research. Students isolate and characterize both the structure and genome of a unique bacteriophage. Students gain experience in basic sterile technique, solution, manipulation of DNA, and bioinformatic analysis of a new genome. Enrollment restricted to first-year students and sophomores. Enrollment by online application and permission of instructor. Enrollment limited to 14. May be repeated for credit. Instructors: Grant Hartzog, Manny Ares
BIOL 100L. Biochemistry Laboratory 5-unit lab offered varying quarters throughout the year.
Basic techniques and principles of laboratory biochemistry including isolation and characterization of a natural product, manipulation of proteins and nucleic acids to demonstrate basic physical and chemical properties; and characterization of enzyme substrate interactions. Students are billed a materials fee. Prerequisite(s): previous or concurrent enrollment in BIOL 100; satisfaction of the Entry Level Writing and Composition requirements. Enrollment restricted to biological sciences and affiliated majors, non-majors by permission of instructor. Enrollment limited to 20. (General Education Code(s): W.) Instructor: Mike Dalbey
BIOL 105L. Eukaryotic Genetics Laboratory 5-unit lab offered varying quarters throughout the year.
Classical and newly developed molecular-genetic techniques used to explore genetic variation in wild populations of the fruit fly Drosophila melanogaster. Topics include Mendelian fundamentals, mapping, design of genetic screens, bio-informatic and database analysis, genetic enhancers, and population genetics. Students are billed a materials fee. Prerequisite(s): BIOL 105; BIOL 100 or BIOC 100A recommended; satisfaction of Entry Level Writing and Composition Requirements. Enrollment restricted to biological sciences and affiliated majors non-majors by permission of instructor. (General Education Code(s): W.) Instructor: Jeremy Lee
BIOL 109L. Yeast Molecular Genetics Laboratory 5-unit lab offered once a year.
The powerful genetic and molecular techniques available for yeast combined with the complete genomic DNA sequence offers opportunity for discovery of fundamental aspects of eukaryotic life. Lab providing practical experience in using yeast as an experimental system. Students are billed a materials fee. Prerequisite(s): BIOL 105; BIOL 115 strongly recommended; satisfaction of the Entry Level Writing and Composition requirements. Enrollment restricted to biological sciences and affiliated majors, non-majors by permission of instructor. Enrollment limited to 15. (General Education Code(s): W.) Instructor: Rohinton Kamakaka
BIOL 110L. Cell Biology Laboratory 5-unit lab offered once a year.
Fundamental aspects of cell biology explored through experimentation in a modern laboratory setting. Research topics include the structure and function of biological membranes; intracellular transport and organelle biogenesis; the cell cycle; and the cytoskeleton. Students are billed a materials fee. Prerequisite(s): BIOL 100 or BIOC 100A; previous or concurrent enrollment in course 110; satisfaction of the Entry Level Writing and Composition requirements. Enrollment restricted to biological sciences and affilitated majors, non-majors by permission. Enrollment limited to 16. (General Education Code(s): W.) Instructor: Michael Rexach
BIOL 115L. Eukaryotic Molecular Biology Laboratory 5-unit lab offered twice a year in Winter and Spring.
A laboratory designed to provide students with direct training in basic molecular techniques. Each laboratory is a separate module which together builds to allow cloning, isolation, and identification of a nucleic acid sequence from scratch. Students cannot receive credit for this course and course 187L or 287L. Students are billed a materials fee. Prerequisite(s): BIOL 100 or BIOC 100A; previous or concurrent enrollment in course 115; satisfaction of the Entry Level Writing and Composition requirements. Enrollment restricted to biological sciences and affiliated majors, non-majors by permission. Enrollment limited to 20. (General Education Code(s): W.) Instructor: Mary Zavanelli
BIOL 119L. Microbiology Laboratory 5-unit lab offered every quarter and in summer.
An introduction to the principles and practices of laboratory microbiology, with a substantial presentation of optical microscopy. Students are billed a materials fee. Prerequisite(s): previous or concurrent enrollment in BIOL 119 is required; satisfaction of Entry Level Writing and Composition requirements. Enrollment restricted to biological sciences and affiliated majors, non-majors by permission of instructor. (General Education Code(s): W.) Instructors: Chad Saltikov, Karen Ottemann, Mike Dalbey
BIOL 120L. Development Laboratory 5-unit lab offered once a year in Winter.
Experimental studies of animal development using a variety of locally obtainable organisms. Approximately eight hours weekly, but it will often be necessary to monitor continuing experiments throughout the week. Previous or concurrent enrollment in course 120 required. Students are billed a materials fee. Prerequisite(s): BIOL 100 or BIOC 100A and BIOL 110. Previous or concurrent enrollment in BIOL 120 required. Enrollment restricted to biological sciences and affiliated majors, non-majors by permission of instructor. Instructor: Jeremy Lee
BIOL 180. Research Programming for Biologists and Biochemists 5-unit lecture offered once a year in Winter.
No programming experience required, but basic computer skills assumed. Students without prior programming experience taught basic proficiency in Perl, BioPerl, and other Perl libraries needed to analyze, transform, and publish biological data. Students required to solve a research problem as a final project. Prerequisite(s): BIOL 20A or BIOL 21A. Concurrent enrollment in BIOL 180L is required. Instructor: Josh Stuart
BIOL 180L. Research Programming for Biologists and Biochemists Laboratory 1-unit lab offered once a year in Winter.
Laboratory sequence illustrating topics covered in course 160. One two-hour laboratory per week. Prerequisite(s): BIOL 20A or BIOL 21A. Concurrent enrollment in BIOL 180 is required. Instructor: Josh Stuart
BIOL 181. Computational Biology Tools 5-unit lab offered twice a year.
Hands-on laboratory geared to teach basic tools used in computational biology (motif searching, primer selection, sequence comparison, multiple sequence alignment, genefinders, phylogenetics analysis, X-ray crystallography software). Web- and Unix-based tools/databases are used. Open to all science students; no prior Unix experience required. Prerequisite(s): BIOE 20B and CHEM 1C. Enrollment limited to 25. Instructor: Dietlind Gerloff
BIOL 186F. Undergraduate Research in MCD Biology 2-unit indepedent study offered every quarter (not summer).
Supervised undergraduate research in laboratory of an MCD biology faculty member accompanied by weekly lectures on ethical and practical scientific issues. Topics include laboratory safety; the scientific method; the collection, treatment, and presentation of data; critical evaluation of scientific literature; scientific misconduct; and peer review. Career issues, including how to apply for admission to graduate and professional schools, also discussed. Prerequisite(s): BIOL 20A and BIOE 20B; at least one of BIOL 100, BIOL 105, or BIOC 100A; and permission of instructor. May be repeated for credit. Instrutor: The MCD Faculty
BIOL 186L. Undergraduate Research in MCD Biology 5-unit indepedent study offered every quarter (not summer).
Supervised undergraduate research in laboratory of an MCD biology faculty member accompanied by weekly lectures on ethical and practical scientific issues. Topics include laboratory safety; the scientific method; the collection, treatment, and presentation of data; critical evaluation of scientific literature; scientific misconduct; and peer review. Career issues, including how to apply for admission to graduate and professional schools, also discussed. Prerequisite(s): satisfaction of the Entry-Level Writing and Composition requirements; courses BIOL 20A and BIOE 20B; at least one of BIOL 100, BIOL 105, or BIOC 100A; and permission of instructor. (General Education Code(s): W.) The MCD Faculty
BIOL 187L. Molecular Biotechnology Laboratory 5-unit lab offered every Fall.
An intensive molecular biology laboratory that presents procedures used in molecular and biotechnology research. Topics and procedures include DNA/RNA isolation, cloning and library construction, southern and northern hybridization, DNA fingerprinting, PCR, manual and automated sequencing, and computer methods for analyzing molecular data. New procedures currently being developed in biotechnology industries are presented by industry representatives. Students cannot receive credit for this course and BIOL 116L or BIOL 287L. Students are billed a materials fee. Prerequisite(s): BIOL 20A, BIOE 20B, BIOE 20C, BIOL 100, and BIOL 110. Enrollment limited to 20. Instructor: Mary Zavanelli
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